PlumX Metrics
Embed PlumX Metrics

Total synthesis of ecteinascidin 743

Journal of the American Chemical Society, ISSN: 1520-5126, Vol: 135, Issue: 37, Page: 13684-13687
2013
  • 62
    Citations
  • 0
    Usage
  • 143
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

Article Description

A straightforward synthesis of ecteinascidin 743 was accomplished from readily available l-glutamic acid as a single chiral source. Our novel synthesis features a concise and convergent approach for construction of the B-ring, consisting of a sequence involving a stereoselective Heck reaction between a diazonium salt and an enamide, oxidative cleavage of the resulting alkene, and intramolecular ortho substitution of the phenol by an aldehyde. © 2013 American Chemical Society.

Bibliographic Details

Kawagishi, Fumiki; Toma, Tatsuya; Inui, Tomohiko; Yokoshima, Satoshi; Fukuyama, Tohru

American Chemical Society (ACS)

Chemical Engineering; Chemistry; Biochemistry, Genetics and Molecular Biology

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know