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Synthesis of 2,3-disubstituted benzo[b]selenophenes via electrophilic cyclization

Journal of Organic Chemistry, ISSN: 0022-3263, Vol: 71, Issue: 6, Page: 2307-2312
2006
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2,3-Disubstituted benzo[b]selenophenes have been prepared by the electrophilic cyclization of various 1-(1-alkynyl)-2-(methylseleno)arenes by Br, NBS, I, ICl, PhSeCl, PhSeBr, and Hg(OAc) . This method tolerates a wide variety of functional groups, including alcohol, ester, nitrile, nitro, and silyl groups, and proceeds under exceptionally mild reaction conditions. © 2006 American Chemical Society.

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