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Short and efficient asymmetric synthesis of (-)-α-conhydrine

Journal of Organic Chemistry, ISSN: 0022-3263, Vol: 72, Issue: 14, Page: 5358-5361
2007
  • 49
    Citations
  • 0
    Usage
  • 5
    Captures
  • 0
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Metrics Details

  • Citations
    49
    • Citation Indexes
      49
  • Captures
    5

Article Description

(Chemical Equation Presented) The short and efficient synthesis of (-)-α-conhydrine was accomplished with 41% overall yield in seven steps and high diastereo- and enantioselectivity. The anti-stereochemistry of the two stereogenic centers has been confirmed by the single-crystal X-ray analysis of an intermediate. © 2007 American Chemical Society.

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