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Facile and efficient synthesis of carbohybrids as stereodivergent druglike small molecules

Journal of Organic Chemistry, ISSN: 0022-3263, Vol: 73, Issue: 8, Page: 3270-3273
2008
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(Chemical Equation Presented) A facile and efficient one-pot synthesis of acyclic polyols fused with pyrazolo[1,5-a]pyrimidines and 1,2,4-triazolo[1,5-a] pyrimidines as novel carbohybrids with regioselectivity was achieved through the condensation of 2-C-formyl glycals with 3-aminopyrazoles and 3-amino-1,2,4-triazoles in excellent yields under the microwave irradiation. © 2008 American Chemical Society.

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