AMPLIFIED multiplexed analysis of DNA by the exonuclease iii-catalyzed regeneration of the target dna in the presence of functionalized semiconductor quantum dots
Nano Letters, ISSN: 1530-6984, Vol: 11, Issue: 10, Page: 4456-4461
2011
- 161Citations
- 71Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations161
- Citation Indexes161
- 161
- CrossRef158
- Captures71
- Readers71
- 71
Article Description
Quantum dots (QDs) functionalized with a black-hole quencher are used as optical tracer for the detection of DNA using exonuclease as a biocatalyst. The binding of the target DNA or of a target/open hairpin complex to the functionalized QDs leads to the exonuclease-stimulated recycling of the target DNA or the target/hairpin complex. This results in the triggering of the luminescence of the QDs that provides a readout signal for the amplified sensing process. By using different-sized QDs, the multiplexed detection of DNAs is demonstrated. © 2011 American Chemical Society.
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