Nardosinanols A-I and lemnafricanol, sesquiterpenes from several soft corals, Lemnalia sp., Paralemnalia clavata, Lemnalia africana, and Rhytisma fulvum fulvum
Journal of Natural Products, ISSN: 0163-3864, Vol: 71, Issue: 3, Page: 375-380
2008
- 43Citations
- 17Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations43
- Citation Indexes43
- 43
- CrossRef37
- Captures17
- Readers17
- 17
Article Description
Ten new sesquiterpenes, nardosinanols A-I (1-9) and lemnafricanol (10), have been isolated from several Kenyan soft corals, i.e., from Lemnalia sp., Paralemnalia clavata, Lemnalia africana, and Rhytisma fulvum fulvum. The structures and relative stereochemistry of these compounds were elucidated by interpretation of MS, COSY (H-H correlations), HSQC, HMBC, and NOESY NMR spectroscopic experiments and in the case of 5 also by chemical transformation to compounds 11 and 12. Nine compounds (1-9) are based on the nardosinane skeleton (1-6 are nardosinanes and 7-9 nornardosinanes). Lemnafricanol (10) possesses a novel tricyclic skeleton. Compounds 3, 7, and 10 were found to be toxic to brine shrimp with LC values of 4.0, 0.35, and 0.32 μM, respectively. © 2008 American Chemical Society and American Society of Pharmacognosy.
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