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Phthalide and isocoumarin derivatives produced by an Acremonium sp. isolated from a mangrove rhizophora apiculata

Journal of Natural Products, ISSN: 0163-3864, Vol: 75, Issue: 5, Page: 853-858
2012
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Article Description

Nine new fungal metabolites, one phthalide derivative, acremonide (1), and eight isocoumarin derivatives, acremonones A-H (2-9), were isolated from the mangrove-derived fungus Acremonium sp. PSU-MA70 together with 10 known compounds. Their structures were determined by NMR analysis. The known 8-deoxytrichothecin and trichodermol exhibited moderate antifungal activity against Candida albicans and Cryptococcus neoformanns, respectively. © 2012 The American Chemical Society and American Society of Pharmacognosy.

Bibliographic Details

Rukachaisirikul, Vatcharin; Rodglin, Aekkachai; Sukpondma, Yaowapa; Phongpaichit, Souwalak; Buatong, Jirayu; Sakayaroj, Jariya

American Chemical Society (ACS)

Chemistry; Biochemistry, Genetics and Molecular Biology; Pharmacology, Toxicology and Pharmaceutics; Medicine

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