Sesquiterpenoids and benzofuranoids from the marine-derived fungus Aspergillus ustus 094102
Journal of Natural Products, ISSN: 0163-3864, Vol: 72, Issue: 10, Page: 1761-1767
2009
- 91Citations
- 40Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations91
- Citation Indexes91
- 91
- CrossRef79
- Captures40
- Readers40
- 40
Article Description
Eight drimane sesquiterpenes (1-8), six isochromane derivatives (9-14), and three known compounds, daldinin B (15), 9α-hydroxy-6β-[(2E,4E,6E)- octa-2,4,6-trienoyloxy]-5α-drim-7-en-11,12-olide (16), and pergillin (17), were isolated from the EtOAc extract of the marine-derived fungus Aspergillus ustus 094102. The structures of the new compounds were elucidated on the basis of spectroscopic analysis. The cytotoxic effects on A549 and HL-60 cell lines were evaluated by SRB and MTT methods. Ustusorane E (13) showed significant cytotoxicity against HL-60 cells with an IC value of 0.13 μM. Ustusolates C (6) and E (8) exhibited moderate cytotoxicity against A549 and HL-60 cells with IC values of 10.5 and 9.0 μM, respectively, and ustusolate A (4) showed weak cytotoxicity against HL-60 and A549 cells with IC values of 20.6 and 30.0 μM, respectively. © 2009 American Chemical Society and American Society of Pharmacognosy.
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