Dialyzable carbosilane dendrimers as soluble supports for the functionalization of pyridine fragments via palladium-catalyzed coupling reactions
Organic Letters, ISSN: 1523-7060, Vol: 7, Issue: 3, Page: 363-366
2005
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Article Description
(Chemical Equation Presented) The use of carbosilane (CS) dendrimers as soluble supports in liquid phase organic synthesis (LPOS) is described. Control of the three key steps is perfectly achieved by covalently binding a pyridine fragment to the soluble support, modifying it via coupling reactions, and releasing it at the end. Nanofiltration (dialysis) allows facile purification of the supported molecules after each step.
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