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Synthesis of the tetracyclic skeleton of the lycopodium alkaloid lycopladine H via a pivotal double hydroformylation/intramolecular reductive amination sequence

Organic Letters, ISSN: 1523-7052, Vol: 17, Issue: 4, Page: 806-808
2015
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Article Description

A synthesis of the complete tetracyclic framework of the structurally unique Lycopodium alkaloid lycopladine H has been accomplished using a strategy involving a double alkene hydroformylation/intramolecular reductive amination to form the azocane and spiro-piperidine moieties of the natural product.

Bibliographic Details

Pradeep S. Chauhan; Joshua R. Sacher; Steven M. Weinreb

American Chemical Society (ACS)

Biochemistry, Genetics and Molecular Biology; Chemistry

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