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Asymmetric direct aldol reactions of pyruvic derivatives

Organic Letters, ISSN: 1523-7060, Vol: 10, Issue: 9, Page: 1775-1778
2008
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Article Description

Simple chiral primary-tertiary diamine-Brønsted acid conjugates such as 1e can effectively catalyze the direct aldol reactions of pyruvic derivatives with excellent syn diastereoselectivities and enantioselectivities, thus functionally mimicking the pyruvate-dependent type I aldolases. © 2008 American Chemical Society.

Bibliographic Details

Luo, Sanzhong; Xu, Hui; Chen, Liujuan; Cheng, Jin-Pei

American Chemical Society (ACS)

Biochemistry, Genetics and Molecular Biology; Chemistry

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