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1,2,3-triazole as a special "X-factor" in promoting hashmi phenol synthesis

Organic Letters, ISSN: 1523-7060, Vol: 12, Issue: 2, Page: 344-347
2010
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Article Description

(Figure presented) PNMR experiments revealed rapid decomposition of the PhPAuTfO complex In the presence of the furan-yne, which resulted In poor reactivity as reported In the literature. Therefore, instead of tuning different ligands (PR), the 1,2,3-triazole was applied as a special X-factor to stabilize the catalyst. The desired phenol products were prepared In excellent yields (1% cat. up to 95% yield) and chemoselectivity (>20:1). © 2010 American Chemical Society.

Bibliographic Details

Chen, Yunfeng; Yan, Wuming; Akhmedov, Novruz G; Shi, Xiaodong

American Chemical Society (ACS)

Biochemistry, Genetics and Molecular Biology; Chemistry

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