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Enantiospecific total synthesis of the squalene synthase inhibitors (-)-CJ-13,982 and its enantiomer from a common intermediate

Journal of Antibiotics, ISSN: 1881-1469, Vol: 71, Issue: 2, Page: 234-239
2018
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Article Description

The total syntheses of both the natural and unnatural enantiomers of the alkyl citrate natural product CJ-13,982 (1) from the common d-ribose-derived acid 6 are described.

Bibliographic Details

Sturgess, Dayna; Chen, Zongjia; White, Jonathan M; Rizzacasa, Mark A

Springer Science and Business Media LLC

Pharmacology, Toxicology and Pharmaceutics

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