In silico method for inferring genotypes in pedigrees
Nature Genetics, ISSN: 1061-4036, Vol: 38, Issue: 9, Page: 1002-1004
2006
- 112Citations
- 123Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations112
- Citation Indexes112
- CrossRef112
- 110
- Captures123
- Readers123
- 123
Article Description
Our genotype inference method combines sparse marker data from a linkage scan and high-resolution SNP genotypes for several individuals to infer genotypes for related individuals. We illustrate the method's utility by inferring over 53 million SNP genotypes for 78 children in the Centre d'Etude du Polymorphisme Humain families. The method can be used to obtain high-density genotypes in different family structures, including nuclear families commonly used in complex disease gene mapping studies. © 2006 Nature Publishing Group.
Bibliographic Details
Springer Science and Business Media LLC
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