PlumX Metrics
Embed PlumX Metrics

Model-based projections of Zika virus infections in childbearing women in the Americas

Nature Microbiology, ISSN: 2058-5276, Vol: 1, Issue: 9, Page: 16126
2016
  • 107
    Citations
  • 0
    Usage
  • 164
    Captures
  • 12
    Mentions
  • 19
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    107
    • Citation Indexes
      107
  • Captures
    164
  • Mentions
    12
    • News Mentions
      7
      • News
        7
    • Blog Mentions
      4
      • Blog
        4
    • References
      1
      • Wikipedia
        1
  • Social Media
    19
    • Shares, Likes & Comments
      19
      • Facebook
        19

Most Recent Blog

Zika epidemic could burn out in 3 years but return after 10

Zika infection during pregnancy can cause babies to be born with microcephaly Mario Tama/Getty By Debora MacKenzie The Zika epidemic could be over in three

Most Recent News

Comprehensive Profiling of Zika Virus Risk with Natural and Artificial Mitigating Strategies, United States.(RESEARCH)

Zika virus is a flavivirus spread by Aedes mosquitoes that for >60 years remained only an esoteric threat to human health (1). However, the recent

Article Description

Zika virus is a mosquito-borne pathogen that is rapidly spreading across the Americas. Due to associations between Zika virus infection and a range of fetal maladies 1,2, the epidemic trajectory of this viral infection poses a significant concern for the nearly 15 million children born in the Americas each year. Ascertaining the portion of this population that is truly at risk is an important priority. One recent estimate 3 suggested that 5.42 million childbearing women live in areas of the Americas that are suitable for Zika occurrence. To improve on that estimate, which did not take into account the protective effects of herd immunity, we developed a new approach that combines classic results from epidemiological theory with seroprevalence data and highly spatially resolved data about drivers of transmission to make location-specific projections of epidemic attack rates. Our results suggest that 1.65 (1.45-2.06) million childbearing women and 93.4 (81.6-117.1) million people in total could become infected before the first wave of the epidemic concludes. Based on current estimates of rates of adverse fetal outcomes among infected women 2,4,5, these results suggest that tens of thousands of pregnancies could be negatively impacted by the first wave of the epidemic. These projections constitute a revised upper limit of populations at risk in the current Zika epidemic, and our approach offers a new way to make rapid assessments of the threat posed by emerging infectious diseases more generally.

Bibliographic Details

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know