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Targeting inflammation in the treatment of type 2 diabetes: Time to start

Nature Reviews Drug Discovery, ISSN: 1474-1784, Vol: 13, Issue: 6, Page: 465-476
2014
  • 592
    Citations
  • 0
    Usage
  • 557
    Captures
  • 2
    Mentions
  • 17
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    592
  • Captures
    557
  • Mentions
    2
    • News Mentions
      2
      • 2
  • Social Media
    17
    • Shares, Likes & Comments
      17
      • Facebook
        17

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Review Description

The role of inflammation in the pathogenesis of type 2 diabetes and associated complications is now well established. Several conditions that are driven by inflammatory processes are also associated with diabetes, including rheumatoid arthritis, gout, psoriasis and Crohn's disease, and various anti-inflammatory drugs have been approved or are in late stages of development for the treatment of these conditions. This Review discusses the rationale for the use of some of these anti-inflammatory treatments in patients with diabetes and what we could expect from their use. Future immunomodulatory treatments may not target a specific disease, but could instead act on a dysfunctional pathway that causes several conditions associated with the metabolic syndrome. © 2014 Macmillan Publishers Limited. All rights reserved.

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