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Current and future perspectives of single-cell multi-omics technologies in cardiovascular research

Nature Cardiovascular Research, ISSN: 2731-0590, Vol: 2, Issue: 1, Page: 20-34
2023
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Review Description

Single-cell technology has become an indispensable tool in cardiovascular research since its first introduction in 2009. Here, we highlight the recent remarkable progress in using single-cell technology to study transcriptomic and epigenetic heterogeneity in cardiac disease and development. We then introduce the key concepts in single-cell multi-omics modalities that apply to cardiovascular research. Lastly, we discuss some of the trending concepts in single-cell technology that are expected to propel cardiovascular research to the next phase of single-cell research.

Bibliographic Details

Tan, Wilson Lek Wen; Seow, Wei Qiang; Zhang, Angela; Rhee, Siyeon; Wong, Wing H; Greenleaf, William J; Wu, Joseph C

Springer Science and Business Media LLC

Biochemistry, Genetics and Molecular Biology; Medicine

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