Comparative genomic analysis of Mycobacterium iranicum UM-TJL against representative mycobacterial species suggests its environmental origin
Scientific Reports, ISSN: 2045-2322, Vol: 4, Issue: 1, Page: 7169
2014
- 10Citations
- 19Captures
- 2Mentions
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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- Citations10
- Citation Indexes10
- 10
- CrossRef8
- Captures19
- Readers19
- 19
- Mentions2
- News Mentions1
- News1
- References1
- Wikipedia1
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Article Description
Mycobacterium iranicum is a newly reported mycobacterial species. We present the first comparative study of M. iranicum UM-TJL and other mycobacteria. We found M. iranicum to have a close genetic association with environmental mycobacteria infrequently associated with human infections. Nonetheless, UM-TJL is also equipped with many virulence genes (some of which appear to be the consequence of transduction-related gene transfer) that have been identified in established human pathogens. Taken all together, our data suggest that M. iranicum is an environmental bacterium adapted for pathogenicity in the human host. This comparative study provides important clues and forms the basis for future functional studies on this mycobacterium.
Bibliographic Details
Springer Science and Business Media LLC
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