Finding cannabinoids in hair does not prove cannabis consumption
Scientific Reports, ISSN: 2045-2322, Vol: 5, Issue: 1, Page: 14906
2015
- 49Citations
- 155Captures
- 4Mentions
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations49
- Citation Indexes48
- 48
- CrossRef45
- Policy Citations1
- Policy Citation1
- Captures155
- Readers155
- 155
- Mentions4
- News Mentions3
- News3
- References1
- Wikipedia1
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Article Description
Hair analysis for cannabinoids is extensively applied in workplace drug testing and in child protection cases, although valid data on incorporation of the main analytical targets, Δ9-tetrahydrocannabinol (THC) and 11-nor-9-carboxy-THC (THC-COOH), into human hair is widely missing. Furthermore, Δ9-tetrahydrocannabinolic acid A (THCA-A), the biogenetic precursor of THC, is found in the hair of persons who solely handled cannabis material. In the light of the serious consequences of positive test results the mechanisms of drug incorporation into hair urgently need scientific evaluation. Here we show that neither THC nor THCA-A are incorporated into human hair in relevant amounts after systemic uptake. THC-COOH, which is considered an incontestable proof of THC uptake according to the current scientific doctrine, was found in hair, but was also present in older hair segments, which already grew before the oral THC intake and in sebum/sweat samples. Our studies show that all three cannabinoids can be present in hair of non-consuming individuals because of transfer through cannabis consumers, via their hands, their sebum/sweat, or cannabis smoke. This is of concern for e.g. child-custody cases as cannabinoid findings in a child's hair may be caused by close contact to cannabis consumers rather than by inhalation of side-stream smoke.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84943261131&origin=inward; http://dx.doi.org/10.1038/srep14906; http://www.ncbi.nlm.nih.gov/pubmed/26443501; https://www.nature.com/articles/srep14906; https://dx.doi.org/10.1038/srep14906; http://www.nature.com/articles/srep14906; http://www.nature.com/articles/srep14906.pdf
Springer Science and Business Media LLC
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