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Dual colour, microarray-based, analysis of 10 000 protease substrates

Chemical Communications, ISSN: 1359-7345, Issue: 38, Page: 3984-3986
2006
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Article Description

A 10 000 member PNA-encoded library of FRET based peptides was synthesised for global analysis of protease cleavage specificity; analysis was achieved using a DNA microarray and consumed minimal quantities of enzyme (60 pmole) and library (3.5 nmole). © The Royal Society of Chemistry 2006.

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