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Programmable protein-protein conjugation via DNA-based self-assembly

Chemical Communications, ISSN: 1364-548X, Vol: 48, Issue: 50, Page: 6226-6228
2012
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Article Description

Protein molecules were precisely arrayed on a designable DNA scaffold close to each other using a DNA aptamer. By adding a chemical cross-linker, the neighboring protein molecules were effectively and covalently cross-linked to each other without losing their activities. © 2012 The Royal Society of Chemistry.

Bibliographic Details

Shimada, Josui; Maruyama, Tatsuo; Kitaoka, Momoko; Yoshinaga, Hisao; Nakano, Koji; Kamiya, Noriho; Goto, Masahiro

Royal Society of Chemistry (RSC)

Chemical Engineering; Materials Science; Chemistry

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