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Efficient inhibition of human papillomavirus 16 L1 pentamer formation by a carboxylatopillarene and a p-sulfonatocalixarene

Chemical Communications, ISSN: 1364-548X, Vol: 50, Issue: 24, Page: 3201-3203
2014
  • 83
    Citations
  • 0
    Usage
  • 32
    Captures
  • 0
    Mentions
  • 27
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    83
  • Captures
    32
  • Social Media
    27
    • Shares, Likes & Comments
      27
      • Facebook
        27

Article Description

Pillarenes and calixarenes showed obvious inhibition of HPV16 L1 pentamer formation via their selective binding to Arg and Lys residues at the monomer interface, which was reversible after the release of cyclic arenes. Pillarenes are more effective than calixarenes in terms of the inhibition efficiency, attributing to the different kinetics and binding affinity. © 2014 Royal Society of Chemistry.

Bibliographic Details

Zheng, Dong-Dong; Fu, Ding-Yi; Wu, Yuqing; Sun, Yu-Long; Tan, Li-Li; Zhou, Ting; Ma, Shi-Qi; Zha, Xiao; Yang, Ying-Wei

Royal Society of Chemistry (RSC)

Materials Science; Chemical Engineering; Chemistry

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