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Oxidative regioselective amination of chromones exposes potent inhibitors of the hedgehog signaling pathway

Chemical Communications, ISSN: 1364-548X, Vol: 51, Issue: 5, Page: 925-928
2015
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Article Description

A transition metal-free, oxidative, regioselective cross-coupling between non-functionalized azoles and chromones at C2-position was developed. A broad reaction scope and further transformation of products were demonstrated. The biological evaluation of products revealed a novel class of hedgehog signaling pathway inhibitors. This journal is

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