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One-step ligand exchange and switching from hydrophobic to water-stable hydrophilic superparamagnetic iron oxide nanoparticles by mechanochemical milling

Chemical Communications, ISSN: 1364-548X, Vol: 52, Issue: 14, Page: 3054-3057
2016
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Article Description

We describe a simple, rapid methodology for the synthesis of water-stable iron oxide nanoparticles (IONPs) compatible with a variety of aqueous buffers, based on mechanochemical milling exchange of covalently bound surface ligands on pre-fabricated oleic acid-protected IONPs. Application of milling for IONP ligand exchange eliminates steps required for transforming hydrophobic into negatively charged, water-soluble superparamagnetic IONPs.

Bibliographic Details

Korpany, Katalin V; Mottillo, Cristina; Bachelder, Jill; Cross, Shoronia N; Dong, Pengcheng; Trudel, Simon; Friščić, Tomislav; Blum, Amy Szuchmacher

Royal Society of Chemistry (RSC)

Chemical Engineering; Materials Science; Chemistry

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