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A simple salicylaldehyde-based fluorescent “turn-on” probe for selective detection of Zn in water solution and its application in live cell imaging

Analytical Methods, ISSN: 1759-9679, Vol: 9, Issue: 7, Page: 1119-1124
2017
  • 32
    Citations
  • 0
    Usage
  • 10
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    32
    • Citation Indexes
      32
  • Captures
    10

Article Description

A simple salicylaldehyde-based fluorescent probe 1 for Zn was prepared. The probe 1 has been proven to be highly selective and very sensitive to Zn, and also shows remarkable fluorescence emission improvement upon combining with Zn in a Tris-HCl buffer system at pH 7.2. The great fluorescence changes of probe 1 after incorporation with Zn are mainly ascribed to the photo-induced electron transfer (PET) mechanism. The experimental results reveal that probe 1 could effectively complex Zn at a molar ratio of about 1 : 1 and the binding constant (K) between probe 1 and Zn was determined to be 3.78 × 10 M. The detection limit (DL) of probe 1 was also calculated to be 5.9 × 10 M. In addition, the probe has been successfully applied to fluorescence imaging in living MCF-7 cells.

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