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Crystallization of citrate-stabilized amorphous calcium phosphate to nanocrystalline apatite: A surface-mediated transformation

CrystEngComm, ISSN: 1466-8033, Vol: 18, Issue: 18, Page: 3170-3173
2016
  • 68
    Citations
  • 0
    Usage
  • 53
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    68
    • Citation Indexes
      68
  • Captures
    53

Article Description

This work explores the mechanisms underlying the crystallization of citrate-functionalized amorphous calcium phosphate (cit-ACP) in two relevant media, combining in situ and ex situ characterization techniques. Results demonstrate that citrate desorption from cit-ACP triggers the surface-mediated transformation to nanocrystalline apatite (Ap). Our findings shed light on the key role of citrate, an important component of bone organic matrix, and the medium composition in controlling the rate of transformation and the morphology of the resulting Ap phase.

Bibliographic Details

Konstantinos Chatzipanagis; Teresa Roncal-Herrero; Matthew Bilton; Roland Kröger; Michele Iafisco; Anna Tampieri; José Manuel Delgado-López

Royal Society of Chemistry (RSC)

Chemistry; Materials Science; Physics and Astronomy

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