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Enantioselective copper catalysed, direct functionalisation of allenes: Via allyl copper intermediates

Chemical Science, ISSN: 2041-6539, Vol: 8, Issue: 8, Page: 5240-5247
2017
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Review Description

The direct functionalisation of allenes under copper catalysis enables efficient access to enantioenriched, densely functionalised molecules. In this review we explore the breadth and depth of a versatile reaction manifold, which involves the element-cupration of allenes to generate allyl copper intermediates that are subsequently coupled with diverse arrays of electrophiles.

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