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N, O-Bidentate ligand-tunable copper(II) complexes as a catalyst for Chan-Lam coupling reactions of arylboronic acids with 1 H-imidazole derivatives

Organic and Biomolecular Chemistry, ISSN: 1477-0520, Vol: 16, Issue: 46, Page: 8984-8988
2018
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Article Description

An efficient procedure for Chan-Lam coupling reactions of arylboronic acids with 1H-imidazole derivatives using N,O-bidentate ligand-tunable copper(ii) complexes as a catalyst under base-free conditions has been developed. This protocol features mild reaction conditions, high yields and compatibility with different functional groups, providing a direct and facile strategy for the construction of C-N bonds and synthesis of heterocyclic compounds.

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