Synthesis and direct comparison of the anticancer activities of phomopsolides D and e and two 7-oxa-/7-aza-analogues
MedChemComm, ISSN: 2040-2511, Vol: 10, Issue: 7, Page: 1205-1211
2019
- 3Captures
Metric Options: CountsSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Captures3
- Readers3
Article Description
The synthesis of two stable phomopsolide natural products (D and E) and two analogues is presented. The cytotoxicities of these four compounds are surveyed and compared across a panel of NCI-cancer cell lines. This analysis found moderate cytotoxicities (2-50 μM) for the majority of the cell lines with phomopsolide D being more active than phomopsolide E and the 7-oxa analogue being commensurately more active than the 7-aza analogue.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85069478051&origin=inward; http://dx.doi.org/10.1039/c9md00121b; http://www.ncbi.nlm.nih.gov/pubmed/31391894; https://xlink.rsc.org/?DOI=C9MD00121B; https://dx.doi.org/10.1039/c9md00121b; https://pubs.rsc.org/en/content/articlelanding/2019/md/c9md00121b
Royal Society of Chemistry (RSC)
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