Applications and potential mechanisms of herbal medicines for rheumatoid arthritis treatment: A systematic review
RSC Advances, ISSN: 2046-2069, Vol: 9, Issue: 45, Page: 26381-26392
2019
- 28Citations
- 28Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations28
- Citation Indexes28
- 28
- CrossRef20
- Captures28
- Readers28
- 28
Review Description
In this review, we systematically discuss the role of traditional Chinese medicine (TCM) in rheumatoid arthritis (RA) disease treatment. TCM classifies the subtypes of RA through its own theoretical method, which is beneficial for more accurate diagnosis and treatment with Chinese herbal medicines (CHMs) that are more suitable for different syndromes. TCM mainly uses a flexible combination of CHMs to play an important role in RA treatment. The main components of these extracts can be subdivided into alkaloids, flavonoids, triterpenes, saponins and other compounds. Using a platform of transgenic and induced arthritis models, we explore the potential mechanisms of TCM against RA with the help of omics analysis techniques and methods. These mechanisms are mainly CHM and its extracts can inhibit RA patients and experimental animal models, including synovitis, vascular proliferation and bone injury; this involves many biological signal exchange targets and pathways. In conclusion, the role of TCM in RA treatment mainly involves reducing the expression and secretion of pro-inflammatory factors, thus decreasing the degree of abnormal immune response.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85071931762&origin=inward; http://dx.doi.org/10.1039/c9ra04737a; http://www.ncbi.nlm.nih.gov/pubmed/35685403; https://xlink.rsc.org/?DOI=C9RA04737A; https://dx.doi.org/10.1039/c9ra04737a; https://pubs.rsc.org/en/content/articlelanding/2019/ra/c9ra04737a
Royal Society of Chemistry (RSC)
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