The affinity of RSK for cylitol analogues of SL0101 is critically dependent on the B-ring: C -4′-hydroxy
Chemical Communications, ISSN: 1364-548X, Vol: 56, Issue: 20, Page: 3058-3060
2020
- 9Citations
- 2Captures
Metric Options: CountsSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations9
- Citation Indexes9
- CrossRef7
- Captures2
- Readers2
Article Description
Five cyclitol analogues of SL0101 with variable substitution at the C-4′ position (i.e., OH, Cl, F, H, OMe) were synthesized. The series of analogues were evaluated for their ability to inhibit p90 ribosomal S6 kinase (RSK) activity. The study demonstrated the importance of the B-ring C-4′ hydroxy group for RSK1/2 inhibition.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85081583373&origin=inward; http://dx.doi.org/10.1039/d0cc00128g; http://www.ncbi.nlm.nih.gov/pubmed/32048692; https://xlink.rsc.org/?DOI=D0CC00128G; https://dx.doi.org/10.1039/d0cc00128g; https://pubs.rsc.org/en/content/articlelanding/2020/cc/d0cc00128g
Royal Society of Chemistry (RSC)
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