Direct access to vicinally functionalized and: N -trifluoroacetylated (bicyclic)ketopiperazines using a readily affordable N-heterocyclic anhydride
Organic and Biomolecular Chemistry, ISSN: 1477-0520, Vol: 18, Issue: 8, Page: 1577-1581
2020
- 1Citations
- 4Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations1
- Citation Indexes1
- CrossRef1
- Captures4
- Readers4
Article Description
Functionalized 2-piperazinones play essential roles as conformationally-constrained peptidomimetics by mimicking inverse γ-turns in peptides. Here, we describe an efficient, scalable, stereoselective, modular, and chemoselective annulation protocol between a novel N-trifluoroacetyl anhydride and several reactive partners, including lactim ethers, imidoyl chlorides, aryl aldimines, and 1,3-azadienes, leading to vicinally functionalized (bicyclic) 2-piperazinones.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85080113831&origin=inward; http://dx.doi.org/10.1039/d0ob00049c; http://www.ncbi.nlm.nih.gov/pubmed/32039416; https://xlink.rsc.org/?DOI=D0OB00049C; https://dx.doi.org/10.1039/d0ob00049c; https://pubs.rsc.org/en/content/articlelanding/2020/ob/d0ob00049c
Royal Society of Chemistry (RSC)
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