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Precision syntheses of poly(NIPAM-alt-HEMA) and effects of the alternating sequence on thermoresponsive behaviors in water

Polymer Chemistry, ISSN: 1759-9962, Vol: 14, Issue: 1, Page: 55-61
2022
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Article Description

In this work, an alternating copolymer of 2-hydroxyethyl methacrylate (HEMA) and N-isopropylacrylamide (NIPAM) [poly(NIPAM-alt-HEMA)] was synthesized via ATRP-based cyclopolymerization of a divinyl monomer carrying a transformable linker and aminolysis transformation of the resulting cyclopolymer with isopropylamine. The selective propagation in the cyclopolymerization leading to the alternating sequence was supported by the reactivity ratios of the two model monomers cut out from the divinyl monomer. The quantitative transformation and the alternating sequence were confirmed by H NMR, FT-IR, and MALDI-TOF-MS. The thus-obtained poly(NIPAM-alt-HEMA) underwent an LCST-type temperature-induced phase transition in water, and the thermoresponsive behavior was different from that of the corresponding statistical copolymers [poly(NIPAM-sta-HEMA)] as well as the homopolymer of NIPAM. The thermoresponsiveness specific to the alternating sequence is likely derived from the structural character that can affect the dehydration behavior, such as no existence of the consecutive NIPAM sequence and the adjacent circumstance of NIPAM units and hydroxy pendants of HEMA.

Bibliographic Details

Xiaoyan Xu; Kentaro Shibata; Makoto Ouchi

Royal Society of Chemistry (RSC)

Chemical Engineering; Biochemistry, Genetics and Molecular Biology; Materials Science; Chemistry

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