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Stimuli-responsive release of active anionophore from RGD-peptide-linked proanionophore

Chemical Communications, ISSN: 1364-548X, Vol: 59, Issue: 85, Page: 12759-12762
2023
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Article Description

Integrin-mediated cellular delivery was attempted to optimize practical applications of hydrophobic ionophores. The potent ionophore preferentially transports H/Cl across the lipid bilayers following a symport mechanism. The RGD-peptide-appended tag was stimulated by glutathione to generate the active ionophore, prompting the transport of Cl under the cellular environment.

Bibliographic Details

Srimayee, Soumya; Badajena, Saumya Ranjan; Akhtar, Nasim; Kar, Mrinal Kanti; Dey, Subhasis; Mohapatra, Purusottam; Manna, Debasis

Royal Society of Chemistry (RSC)

Materials Science; Chemical Engineering; Chemistry

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