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Construction of unsymmetrical heterobiaryls via the Cp*Rh(iii)-catalysed C-H/C-H coupling of heteroarenes

Chemical Communications, ISSN: 1364-548X, Vol: 59, Issue: 63, Page: 9646-9649
2023
  • 10
    Citations
  • 0
    Usage
  • 3
    Captures
  • 0
    Mentions
  • 3
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    10
    • Citation Indexes
      10
  • Captures
    3
  • Social Media
    3
    • Shares, Likes & Comments
      3
      • Facebook
        3

Article Description

Herein, a concise method for the Rh(iii)-catalyzed, directing-group-assisted C-H/C-H cross-coupling of N-heterocycles (quinolines, indolines, indoles, pyridines, pyrimidines, pyrazoles) with other heteroarenes (benzoxazoles, benzofurans, and thiophenes) is disclosed for the synthesis of unsymmetrical heterobiaryl compounds in good to excellent yields. A plausible catalytic cycle has been delineated based on experimental and computational mechanistic studies.

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