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Dynamic monitoring of an enzymatically driven dissipative toehold-mediated strand displacement reaction

Chemical Communications, ISSN: 1364-548X, Vol: 60, Issue: 5, Page: 570-573
2023
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Article Description

A general strategy to program self-resettable and dissipative toehold-mediated strand displacement reactions was proposed, using DNA strands as the fuel and lambda exonuclease as the fuel-consuming unit. This non-equilibrium system is reversible and temporally controllable. Furthermore, it can be well integrated into a DNA network to temporally control its cascade reaction or dynamic behaviour.

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