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Visible-light-promoted tandem radical difunctionalization of olefinic amides: a direct access to NO-containing benzoxazines and oxazolines

New Journal of Chemistry, ISSN: 1369-9261, Vol: 47, Issue: 44, Page: 20253-20256
2023
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Article Description

A visible-light-promoted nitration/cyclization of olefinic amides has been developed using N-nitrosuccinimide as a nitrating agent under mild conditions. The reaction involves a radical cascade process to form new C-N and C-O bonds. The present approach allows the synthesis of a variety of useful NO-containing benzoxazines and oxazolines in good yields. This operationally simple protocol possesses good functional group tolerance and a wide range of substrate scope.

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