PlumX Metrics
Embed PlumX Metrics

Phytochemical and pharmacological studies on the acetonic extract of Marrubium globosum ssp. libanoticum

Planta Medica, ISSN: 0032-0943, Vol: 72, Issue: 6, Page: 575-578
2006
  • 26
    Citations
  • 0
    Usage
  • 13
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

Article Description

A new natural labdane diterpene, marrulibanoside, was isolated from the acetonic extract of aerial parts of M. globosum Montbr. et Auch. ex Benth. ssp. libanoticum Boiss. (Lamiaceae). Its structure was determined by spectroscopic methods such as ID and 2D NMR and mass spectrometry. Pharmacological studies have shown that the extract of M. globosum exerts anti-inflammatory effects in the rat paw oedema induced by carrageenin resulting in reduced paw swelling. This activity, which seems due to marrulibanoside, is a consequence of iNOS and COX-2 activities inhibition. © Georg Thieme Verlag KG Stuttgart.

Bibliographic Details

Rigano, Daniela; Grassia, Armando; Borrelli, Francesca; Aviello, Gabriella; Piozzi, Franco; Bruno, Maurizio; Arnold, Nelly Apostolides; Capasso, Raffaele; Senatore, Felice

Georg Thieme Verlag KG

Chemistry; Biochemistry, Genetics and Molecular Biology; Pharmacology, Toxicology and Pharmaceutics; Medicine

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know