Electro-generation of single femtoliter- and picoliter-volume aqueous droplets in microfluidic systems
Applied Physics Letters, ISSN: 0003-6951, Vol: 87, Issue: 3
2005
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Article Description
This letter presents a new method to generate individual femtoliter- to picoliter-volume aqueous droplets in oil using single voltage pulses. With high-speed imaging, we characterized the displacement of the water-oil interface as a function of the time and amplitude of the voltage pulse. At high voltages where jetting and droplet formation occurred, we observed the ratio of droplet-to-jet diameter to be ~1.84, which suggested Rayleigh instability as the primary mechanism responsible for droplet breakup. Droplets with volumes ranging from 14 fl to 8 pl were produced using this method. © 2005 American Institute of Physics.
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