High-force NdFeB-based magnetic tweezers device optimized for microrheology experiments
Review of Scientific Instruments, ISSN: 0034-6748, Vol: 83, Issue: 5, Page: 053905
2012
- 20Citations
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Review Description
We present the design, calibration, and testing of a magnetic tweezers device that employs two pairs of permanent neodymium iron boron magnets surrounded by low-carbon steel focusing tips to apply large forces to soft materials for microrheology experiments. Our design enables the application of forces in the range of 1-1800 pN to ∼4.5 μm paramagnetic beads using magnet-bead separations in the range of 0.3-20 mm. This allows the use of standard coverslips and sample geometries. A high speed camera, custom LED-based illumination scheme, and mechanically stabilized measurement platform are employed to enable the measurement of materials with viscoelastic moduli as high as ∼1 kPa. © 2012 American Institute of Physics.
Bibliographic Details
AIP Publishing
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