A microfluidic device to study cancer metastasis under chronic and intermittent hypoxia
Biomicrofluidics, ISSN: 1932-1058, Vol: 8, Issue: 5, Page: 054117
2014
- 52Citations
- 82Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations52
- Citation Indexes52
- 52
- CrossRef46
- Captures82
- Readers82
- 82
Article Description
Metastatic cancer cells must traverse a microenvironment ranging from extremely hypoxic, within the tumor, to highly oxygenated, within the host's vasculature. Tumor hypoxia can be further characterized by regions of both chronic and intermittent hypoxia. We present the design and characterization of a microfluidic device that can simultaneously mimic the oxygenation conditions observed within the tumor and model the cell migration and intravasation processes. This device can generate spatial oxygen gradients of chronic hypoxia and produce dynamically changing hypoxic microenvironments in long-term culture of cancer cells.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84908122789&origin=inward; http://dx.doi.org/10.1063/1.4898788; http://www.ncbi.nlm.nih.gov/pubmed/25584114; https://pubs.aip.org/bmf/article/8/5/054117/386233/A-microfluidic-device-to-study-cancer-metastasis; http://scitation.aip.org/content/aip/journal/bmf/8/5/10.1063/1.4898788; http://scitation.aip.org/limit_exceeded.html
AIP Publishing
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