Diastolic filling abnormalities by color kinesis in newborns exposed to intrauterine cocaine
Journal of the American Society of Echocardiography, ISSN: 0894-7317, Vol: 15, Issue: 5, Page: 447-453
2002
- 14Citations
- 12Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations14
- Citation Indexes14
- CrossRef14
- 12
- Captures12
- Readers12
- 12
Article Description
Because cocaine crosses the placenta, we prospectively evaluated global and segmental systolic and diastolic cardiac function by color kinesis in clinically asymptomatic newborns who were exposed to cocaine in utero (group 1, n = 82). Their data were compared with normal controls (group 3, n = 87) and newborns exposed to drugs other than cocaine (group 2, n = 108). During left ventricular filling, newborns exposed to cocaine, compared with groups 2 and 3, had significantly ( P <.05) higher global fractional area change (%) (76 ± 10.3 vs 72 ± 9.4 and 72 ± 9.1, respectively), regional fractional area changes (%) for the anterior, septal, inferior, and lateral wall, and in the index of asynchrony (at 50% filling 13.2 ± 5.8 vs 11.3 ± 4.1 and 11.6 ± 4.2, respectively). There were no significant differences in systolic function among the 3 groups. Prenatal cocaine exposure in asymptomatic infants leads to higher global and segmental fractional area changes and asynchrony during diastole. The significance and course of these alterations require further investigation. (J Am Soc Echocardiogr 2002;15:447-53.)
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S089473170228548X; http://dx.doi.org/10.1067/mje.2002.117296; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0036583029&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/12019428; https://linkinghub.elsevier.com/retrieve/pii/S089473170228548X; https://dx.doi.org/10.1067/mje.2002.117296
Elsevier BV
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