Peptide-Centric Proteome Analysis: An Alternative Strategy for the Analysis of Tandem Mass Spectrometry Data *
Molecular & Cellular Proteomics, ISSN: 1535-9476, Vol: 14, Issue: 9, Page: 2301-2307
2015
- 127Citations
- 334Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations127
- Citation Indexes126
- 126
- CrossRef101
- Patent Family Citations1
- Patent Families1
- Captures334
- Readers334
- 334
Article Description
In mass spectrometry-based bottom-up proteomics, data-independent acquisition is an emerging technique because of its comprehensive and unbiased sampling of precursor ions. However, current data-independent acquisition methods use wide precursor isolation windows, resulting in cofragmentation and complex mixture spectra. Thus, conventional database searching tools that identify peptides by interpreting individual tandem MS spectra are inherently limited in analyzing data-independent acquisition data. Here we discuss an alternative approach, peptide-centric analysis, which tests directly for the presence and absence of query peptides. We discuss how peptide-centric analysis resolves some limitations of traditional spectrum-centric analysis, and we outline the unique characteristics of peptide-centric analysis in general.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S1535947620326396; http://dx.doi.org/10.1074/mcp.o114.047035; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84940553225&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/26217018; http://www.mcponline.org/lookup/doi/10.1074/mcp.O114.047035; https://syndication.highwire.org/content/doi/10.1074/mcp.O114.047035; https://linkinghub.elsevier.com/retrieve/pii/S1535947620326396; https://dx.doi.org/10.1074/mcp.o114.047035; http://www.mcponline.org/content/14/9/2301; http://www.mcponline.org/content/14/9/2301.abstract; http://www.mcponline.org/content/14/9/2301.full.pdf; https://www.mcponline.org/content/14/9/2301; https://www.mcponline.org/content/14/9/2301.abstract; https://www.mcponline.org/content/mcprot/14/9/2301.full.pdf
American Society for Biochemistry & Molecular Biology (ASBMB)
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