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Genetic polymorphisms of osteopontin (OPN), prolactin (PRL) and pituitary-specific transcript factor-1 (PIT-1) in South Anatolian and East Anatolian Red cattle

Acta Agriculturae Scandinavica A: Animal Sciences, ISSN: 0906-4702, Vol: 58, Issue: 2, Page: 109-112
2008
  • 20
    Citations
  • 0
    Usage
  • 10
    Captures
  • 2
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    20
    • Citation Indexes
      20
  • Captures
    10
  • Mentions
    2
    • News Mentions
      2
      • News
        2

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Association of Single-Nucleotide Polymorphisms of MDR1 and OPN Genes with Reproductive Traits in Different Breeds of Sows

Key words: MDR1, OPN, Single-nucleotide Polymorphism, Reproductive traits, Sows INTRODUCTION Reproductive traits, especially litter traits, are one of the most economically important parameters in pig

Article Description

The objective of the present study was to determine the genotype and allele frequencies for osteopontin (OPN), prolactin (PRL) and pituitary-specific transcription factor-1 (PIT-1) that are claimed to be associated with milk production traits in cattle in South Anatolian Red (SAR) and East Anatolian Red (EAR) cattle. In this study, 40 cattle for each of SAR and EAR were used. OPN in intron 4, PRL in exon 3 and PIT-1 in exon 6 were amplified by polymerase chain reaction (PCR) and the resulting PCR products were subjected to digestion using BseNI, RsaI and HinfI enzymes, respectively, to determine the single nucleotide polymorphisms (SNPs). Results showed that frequencies of the OPN allele C, PRL allele B, and PIT-1 allele A which are associated with milk production tarits were found low in SAR and EAR. As a result, SAR and EAR cattle breeds have the lower allel frequencies that influence the milk production traits for three genes than high-yielding European dairy cattle breeds.

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