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A new cytotoxic homoisoflavonoid from Dracaena cambodiana

Journal of Asian Natural Products Research, ISSN: 1028-6020, Vol: 11, Issue: 2, Page: 192-195
2009
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Article Description

A new homoisoflavonoid, named cambodianol (1), together with the two known flavanes, (2S)-7,3′-dihydroxy-4′-methoxy-8-methylflavane (2) and (2R)-7,4′-dihydroxy-8-methylflavane (3), were isolated from the stems of Dracaena cambodiana. Their structures were determined based on HR-ESI-MS and spectroscopic techniques (UV, IR, 1D-, and 2D-NMR). Compound 1 exhibited significant cytotoxic activities against K562 and SGC-7901 with the IC50 values of 1.4 and 2.9 μg/ml, respectively. © 2009 Taylor & Francis.

Bibliographic Details

Liu, Jian; Mei, Wen-Li; Wu, Jiao; Zhao, You-Xing; Peng, Ming; Dai, Hao-Fu

Informa UK Limited

Chemistry; Biochemistry, Genetics and Molecular Biology; Pharmacology, Toxicology and Pharmaceutics; Medicine

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