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Thio analogues of pyrimidine bases: Syntheses and spectral study of new potentially biologically active 2,4-di-ortho-(meta- and para-)bromo- (chloro and nitro)-benzylthio-5-bromouracils (and 6-methyluracils)

Phosphorus, Sulfur and Silicon and the Related Elements, ISSN: 1042-6507, Vol: 185, Issue: 7, Page: 1429-1436
2010
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Article Description

Eighteen new 2,4-di-ortho- (meta- and para-) bromo-(chloro- and nitro-)benzylthio-5-bromouracils (and 6-methyluracils) have been prepared. The structures of these compounds were confirmed by spectral (IR, UV/vis, 1H NMR) and elemental analyses. Estimation of pharmacotherapeutic potential has been made for synthesized compounds on the basis of prediction of activity spectra for substances (PASS). Copyright © Taylor & Francis Group, LLC.

Bibliographic Details

Grazyna Bartkowiak; Elzbieta Wyrzykiewicz; Grzegorz Schroeder; Anna Walkowiak; Anna Szponar; Ilona Pawlak

Informa UK Limited

Biochemistry, Genetics and Molecular Biology; Chemistry

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