Fetal and Placental Pathology in Congenital Syphilis: A Comprehensive Study in Perinatal Autopsy
Fetal and Pediatric Pathology, ISSN: 1551-3823, Vol: 37, Issue: 4, Page: 231-242
2018
- 11Citations
- 36Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations11
- Citation Indexes11
- 11
- CrossRef9
- Captures36
- Readers36
- 36
Article Description
Introduction: At autopsy, without available serologic information, diagnosing congenital syphilis (CS) relies on identification of Treponema pallidum in tissues. Recognition of clues leading to detection of the organism is important. Materials and methods: Autopsy cases with CS were studied for fetal and placental abnormalities. Results: Twenty-one cases were recruited: 12/21 with identifiable T. pallidum and 9/21 with positive serology and characteristics of CS. 20/21 (95%) demonstrated ≥1 fetal abnormalities. Chronic stress involution of thymus was most common. Hydrops and hepatosplenomegaly were found in >50%. Metaphyseal abnormalities and organ inflammation were found in <30%. Mucocutaneous lesions were lacking. Placental abnormalities were identified in 20/21 (95%). Placentomegaly was most common. Amniotic fluid infection (AFI) was noted in >50%. Conclusion: Common findings in CS at autopsy include chronic stress involution of thymus, hydrops, and hepatosplenomegaly. Mucocutaneous lesions are uncommon. Common placental findings in fetal deaths due to CS include placentomegaly and AFI.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85053300961&origin=inward; http://dx.doi.org/10.1080/15513815.2018.1485798; http://www.ncbi.nlm.nih.gov/pubmed/30207805; https://www.tandfonline.com/doi/full/10.1080/15513815.2018.1485798; https://dx.doi.org/10.1080/15513815.2018.1485798
Informa UK Limited
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