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Dissecting the molecular landscape of pancreatic cancer: towards a precision medicine approach

Expert Review of Precision Medicine and Drug Development, ISSN: 2380-8993, Vol: 4, Issue: 3, Page: 113-119
2019
  • 4
    Citations
  • 0
    Usage
  • 12
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    4
    • Citation Indexes
      4
  • Captures
    12

Article Description

Introduction: Pancreatic cancer is a highly malignant disease with an increasing incidence. Most patients with this type of neoplasm present with unresectable tumors at the time of diagnosis. Areas covered: Current treatments for such patients are minimally effective in controlling cancer progression; therefore, alternative therapeutic approaches are needed to improve clinical outcomes. Thanks to the growing body of knowledge on the genetic landscape of pancreatic cancer, the application of the so-called ‘precision medicine’, a new approach that considers the individual variability in molecular alterations to improve oncological outcomes by personalizing cancer treatment, could be now possible for some patients. Expert opinion: In this review, we will discuss the most recent investigative studies, as well as their primary results, of the potential role of precision medicine in the treatment of pancreatic cancer.

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