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Analysis of the RB1 gene in children with retinoblastoma having residential connections to West Cumbria, England

Journal of Radiological Protection, ISSN: 0952-4746, Vol: 25, Issue: 1, Page: 89-92
2005
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Article Description

Six of eight cases of retinoblastoma previously identified as having a residential association with West Cumbria, England, in which the Sellafield nuclear installation is situated, were examined for the presence of a constitutional RB1 mutation. No mutations were detected, thus providing strong evidence against an environmental or occupational genotoxic effect causing germline mutations in the parents of these children. © 2005 IOP Publishing Ltd.

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