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Temperature monitoring during light-induced release of cargo using polymer capsules modified with gold nanoparticles and nanodiamonds

Journal of Physics: Conference Series, ISSN: 1742-6596, Vol: 2015, Issue: 1
2021
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Conference Paper Description

Application of different light-sensitive drug delivery carriers is limited due to a risk of overheating of living cells. Therefore, a real-time temperature monitoring within biological objects that controls the photothermal release of different cargos from light-sensitive carriers is highly demanded. In this work, we develop a multifunctional platform comprised of polymer microcapsules modified with nitrogen vacancies (NV) centers as nanothermometers and gold (Au) nanoparticles (NPs) as heating elements for the realization of laser-induced cargo release with a simultaneous temperature measurement inside cells. Such platform allows to prevent unwanted side effects related with the overheating of living cells and tissues.

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